Kiwof Plus For Dogs® (Praziquantel, Pyrantel Pamoate, Febantel)

Kiwof Plus Chewable tablets for Small, Medium, Large Dogs

What is Kiwof Plus used for?

Kiwof Plus Easy Chew tablets 50/144/50 are used as a multi spectrum de-wormer for dogs only, and are suitable for small, medium and large dogs, but nor for puppies or cats.  Kiwof Plus Easy Chews are effective in the control of all common gastrointestinal worms. These include the roundworms (ascarids) Toxicara canis and Toxascaris leonine; the hookworms Ancylostoma caninum and Uncinaria stenocephala; and the whipworm Trichuris vulpis.  They are also effective against intestinal tapeworms (cestodes), including Dipylidium caninum, Taenia taeniaformis, Echinococcus granulosus, and Echincoccus multilocularis, and for removal and control of the hyatid cyst, which is the larval form of the tapeworm.  Kiwof Plus Easy Chews can also be used in combination with other treatments such as medications for the prevention of heartworm, fleas and ticks; also, vaccinations, but should not be used in combination with other deworming medications.  Kiwof Plus Easy Chews can be given directly to your dog or disguised in food and are easy to use.

How does Kiwof Plus work?

Kiwof Plus Easy Chew tablets 50/144/50 contain a combination of three anthelmintic drugs, which is a drug that kills and dispels parasitic worms (helminths).  Praziquantel in Kiwof Plus Easy Chews is an anthelmintic that is effective against intestinal tapeworms (cestodes) and works by interfering with the tapeworm’s ability to protect itself against its host, causing the tapeworm to lose resistance to digestion by the host’s digestive enzymes.  The tapeworm becomes disintegrated and is then removed by the host’s immune system, which destroys the tapeworm before it can be passed out in stools.  Pyrantel in Kiwof Plus Easy Chews is a depolarising neuromuscular blocking agent that is effective against roundworms and hookworms that attach to the wall of the host’s intestine by small teeth or suckers.  It works by blocking nerve transmission causing sudden muscular contraction followed by paralysis.  This causes the worm to lose its grip on the intestine wall and fall off; it then becomes paralysed and dies and is passed out in the stools.  Febantel in Kiwof Plus Easy Chews is inactive but is converted to fenbendazole a benzimidazole anthelmintic, which has a broad spectrum action.  Fenbendazole works by binding to tubulin in the worm cells, a structural protein of microtubules, and this blocks glucose uptake, which depletes energy stores and eventually paralyses the parasite, which then dies.  Although these drugs are effective against parasitic worms in the intestine, they are not well absorbed into the blood of the host and therefore, have minimal side effects.

What does Kiwof Plus contain?

Kiwof Plus Easy Chews contain a combination of three active ingredients, the anthelmintic drugs praziquantel (50mg) pyrantel pamoate (144mg), febantel (150mg) that are used in combination as a multi spectrum de-wormer for dogs of all sizes.

What are the side effects of Kiwof Plus?

The most commonly reported side effects when taking Kiwof Plus include vomiting, diarrhoea and lethargy.

When should Kiwof Plus not be used?

You should not give Kiwof Plus to your dog if your dog:

• is allergic to praziquantel, pyrantel pamoate, febantel or any ingredients in Kiwof Plus
• is pregnant, without discussion with your veterinarian
• is taking a piperazine deworming medication
• is still a puppy

How should Kiwof Plus be used?

You should give your dog one dose of Kiwof Plus Easy Chew tablets directly by hand or added to their food, and no starvation is needed before or after treatment. You should repeat the treatment once every 3 months for as long as recommended by your veterinarian professional, to prevent recurrence of infection.  If your dog has a heavy roundworm infestation you can give a repeat dose after 14 days.
The dose you give should depend on your dog’s body weight.  Each treatment, which may be up to 4 tablets, should be given as a single dose.  The recommended dose rate is 15 mg/kg febantel, 14.4 mg/kg pyrantel and 5mg/kg praziquantel, which is equivalent to one tablet per 10kg body weight.

Small dogs

• 3-5kg (6.6-11lbs) - half tablet
• 5-10kg (11-22lb) -   one tablet

Medium dogs

• 10kg-15kg (22-33lbs) - one and a half tablet
• 15-20kg (33-44lb) - two tablets
• 20-25kg (44-55lb) - two and a half tablets
• 25-30kg (55-66lb) - three tablets

Large dogs

• 30-35kg (66-77lb) - three and a half tablets
• 35-40kg (77-88lb) - four tablets

How long should you give Kiwof Plus?

You should give your dog the appropriate dose for their body weight of Kiwof Plus Easy Chew tablets for as long as recommended by your veterinarian professional, to prevent recurrence of infection.

Missed dose of Kiwof Plus

If you miss a dose of Kiwof Plus Easy Chew tablets give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Kiwof Plus be stored?

You should store your Kiwof Plus below 25°C in a cool dry place and protect from light.